منابع مشابه
[Mechanism underlying thrombus formation in cerebral infarction].
For thrombus formation, three important factors, blood flow, blood component and blood vessels, have been recognized as Virchow's triad. In cardiogenic embolism with atrial fibrillation, stagnation of blood in the left atrium causes fibrin-rich thrombus. Anticoagulation is the only effective drug for prevention of this type of thrombus. In atherothrombotic and lacunar infarction, injury of endo...
متن کاملMicrofacies, geochemical characters and possible mechanism of rhythmic deposition of the Pabdeh Formation in SE Ilam (SW Iran)
Rhythmical alternations between limestone and marls characterize the Pabdeh Formation, southwestern Iran. Three intervals of these rhythmites were studied using sedimentary, petrography and geochemical parameters analysis, to unravel the possible mechanisms responsible for the origin of these rhythmites. The microfacies analysis reflects calm deep-water sedimentation that were interrupted by sp...
متن کاملMechanisms of thrombus formation.
N Engl J Med 2008;359:938-49. Copyright © 2008 Massachusetts Medical Society. Hemostasis is the process that maintains the integrity of a closed, high-pressure circulatory system after vascular damage. Vessel-wall injury and the extravasation of blood from the circulation rapidly initiate events in the vessel wall and in blood that seal the breach. Circulating platelets are recruited to the sit...
متن کاملThrombus formation reimagined.
In 1882, Dr Giulio Bizzozero described the use of intravital microscopy to detect the accumulation of platelets following needleinduced injury of the mesenteric artery in rabbits and guinea pigs. Bizzozero’s paper was not only the first to define the platelet in name (“Blutplättchen” in German) but was also the first to functionally define platelets as the primary cell type contributing to thro...
متن کاملPlatelet Thrombus Formation
severe homozygous von Willebrand factor (vWF)-deficient pigs (vWF<3%) (n=6), and heterozygous vWF-deficient pigs (vWF=24%) (n=2). Thrombus formation was measured by autologous "'In-platelet labeling and by ultrastructural morphology. Heparinized and native blood from these pigs was perfused over the substrate for 3 and 5 minutes at local shear rates from 212 to 3,380/sec. On collagen type I exp...
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ژورنال
عنوان ژورنال: Nature
سال: 1966
ISSN: 0028-0836,1476-4687
DOI: 10.1038/209298a0